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・ WAGR L class (diesel)
・ WAGR M class
・ WAGR M class (1875)
・ WAGR M class (diesel)
・ WAGR Msa class
・ WAGR N class
・ WAGR O class
・ WAGR P and Pr classes
・ WAGR Pm and Pmr classes
・ WAGR Q class
・ WAGR Q class (1895)
・ WAGR R class
・ WAGR R class (diesel)
・ WAGR S class
・ WAGR S class (1888)
WAGR syndrome
・ WAGR T class
・ WAGR T class (diesel)
・ WAGR U class
・ WAGR U class (1903)
・ WAGR V class
・ WAGR W class
・ WAGR WCA/WCE class
・ WAGR X class
・ WAGR Y class
・ WAGR Z class
・ WAGR-FM
・ Wagrain
・ Wagram (disambiguation)
・ Wagram (Paris Métro)


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WAGR syndrome : ウィキペディア英語版
WAGR syndrome

WAGR syndrome is a rare genetic syndrome in which affected children are predisposed to develop Wilms tumour (a tumour of the kidneys), Aniridia (absence of the coloured part of the eye, the iris), Genitourinary anomalies, and Retardation. The G is sometimes instead given as "gonadoblastoma," since the genitourinary anomalies are tumours of the gonads (testes or ovaries).
A subset of WAGR syndrome patients shows severe childhood obesity; the acronym WAGRO (O for obesity) has been used to describe this category.
The condition results from a deletion on chromosome 11 resulting in the loss of several genes. As such, it is one of the best studied examples of a condition caused by loss of neighbouring (contiguous) genes.〔
==Synonyms==
WAGR complex, Wilms tumour-aniridia syndrome, aniridia-Wilms tumour syndrome.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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